Cryptotanshinone是什么

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August undefined, 2024

WebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured …

Cryptotanshinone = 98 HPLC 35825-57-1 - Sigma-Aldrich

WebAug 13, 2024 · Hepatocellular carcinoma (HCC) is a fatal and dominant form of liver cancer that currently has no effective treatment or positive prognosis. In this study, we explored the antitumor effects of cryptotanshinone (CPT) against HCC and the molecular mechanisms underlying these effects using a systems pharmacology and experimental validation … WebBackground and purpose: Cryptotanshinone (CTS) is a major bioactive diterpenoid isolated from Danshen, an eminent medicinal herb that is used to treat cardiovascular disorders … hidrofulgantes

Cryptotanshinone = 98 HPLC 35825-57-1

Web35825-57-1 Cryptotanshinone: Cryptotanshinone, a natural cell-permeable diterpene quinone isolated from Salvia miltiorrhiza, it inhibits acetylcholinesterase (IC50 = 4.09 mM) and reduces A peptide generation so that can treat Alzheimer's disease. It also inhibits STAT3 activity (IC Implicated in Alzheimer's disease WebCryptotanshinone (CTS) is a natural compound involved in antioxidant and anti-inflammatory activities. We evaluated the effects of CTS on inflammation and oxidative stress in obstructed kidneys. Mice received gastric gavage of CTS from 7 days before unilateral ureteral obstruction operation to 1 week after surgery. Administration of CTS at … WebTanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) … hidrogea gestion

A Mechanistic Study of the Intestinal Absorption of Cryptotanshinone …

Synergistic Effects of Cryptotanshinone and Senkyunolide I in ...

WebNational Center for Biotechnology Information WebAug 13, 2024 · Cryptotanshinone (CPT), an active compound isolated from Radix Salviae Miltiorrhizae, has been reported to possess diverse pharmacological activities, including … how far can a train horn travelWebProvided are a composition for stimulating differentiation of MSCs into osteoblasts, which includes cryptotanshinone, and an osteogenesis stimulator including cryptotanshinone and MSCs. When the cryptotanshinone is treated to the MSCs, the differentiation into osteoblasts is stimulated, and thus osteogenesis of a patient may be stimulated by … hidrofugo o hidrofobo

"WebCryptotanshinone is a natural quinoid diterpene first isolated from Salvia miltiorrhiza roots, which are used in traditional Chinese medicine for a variety of conditions. 1 Cryptotanshinone, at 10-20 µM, stimulates AMP-activated protein kinase in C2C12 myotubes and activates p38 MAPK in DU145 cells.2,3 It inhibits " - Cryptotanshinone是什么

Cryptotanshinone是什么

Synergistic Effects of Cryptotanshinone and Senkyunolide I in ...

Web2.4 Antitumor. Tanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) inhibiting the invasion, migration and ... http://www.thegoodscentscompany.com/data/rw1665471.html

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WebSep 16, 2016 · Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with … WebMar 31, 2014 · Cryptotanshinone is one of the compounds extracted from the root of Salvia miltiorrhiza Bunge. Unlike other tanshinones, only a small number of studies have focused on cryptotanshinone for medical treatment. In the present study, the A549 lung cancer cell line and xenograft models of human lung tumors were used to assess the anti‑cancer …

WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation through a JAK2-independent mechanism. Cryptotanshinone selectively inhibits STAT3 ... WebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on …

WebJul 1, 2024 · Abstract. Cryptotanshinone is a diterpene quinone derived from the roots of Salvia miltiorrhiza Bunge. An increasing number of studies have demonstrated that cryptotanshinone has the pharmacological activities such as anti-oxidative stress, anti-bacteria, anti-inflammation, and anti-cancer. Cryptotanshinone has been found to … WebCryptotanshinone 是一种STAT3抑制剂，无细胞试验中IC50为4.6 μM，强烈抑制STAT3 Tyr705磷酸化，对STAT3 Ser727作用效果弱，对STAT1和STAT5没有作用效果 …

WebCryptotanshinone is a quinoid diterpene isolated from the root of the Asian medicinal plant, Salvia miotiorrhiza bunge. Recently it was discovered that the compound is a potent …

WebCryptotanshinone; Cryptotanshinone. Catalog No. N1843. Add to Compare. Email. STAT3/AChE inhibitor. Skip to the end of the images gallery. Skip to the beginning of the … how far can a tsunami travel in californiaWebCryptotanshinone: A review of its pharmacology activities and molecular mechanisms. As a natural quinone compound, the medicinal value of cryptotanshinone (CT) has received increasing attentions, but there is no systematic literature review that describes the … how far can a tree frog jumpWebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none … how far can a tsunami travel across the oceanWebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. … how far can a tsunami travelWebThe nature of intestinal absorption of most herbal medicine is unknown. Cryptotanshinone (CTS) is the principal active constituent of the widely used cardiovascular herb Salvia miltiorrhiza (Danshen). We investigated the oral bioavailability of CTS in rats and the mechanism for its intestinal absorption using several in vitro and in vivo models: 1) Caco … hidrogeofisicaWebSep 16, 2016 · Cryptotanshinone reverses the ovarian IR and significantly increases 2-deoxy-D-[1,2-3 H]-glucose uptake in all examined tissues from the DEX-treated mice.Cryptotanshinone significantly reduces the … hidrogea ceheginWebJan 14, 2024 · Guanxinning Tablet, a modern Chinese drug which contains extracts of the two herbs, also showed strong therapeutic effects in coronary heart disease. However, … hidrogel oftalmico