Daptomycin induced kidney injury

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August undefined, 2024

WebMar 10, 2024 · Levofloxacin is used for mild-to-moderate infections, the typical indications including sinusitis, bronchitis, community acquired pneumonia, skin infections, urinary tract infections, pyelonephritis, … WebStudy objective: Daptomycin is a therapeutic option for patients with underlying renal insufficiency who are vulnerable to nephrotoxicity from vancomycin. We evaluated …

Efficacy and safety of daptomycin in patients with renal

WebMay 20, 2024 · The aim of the study was to evaluate whether patients treated for Gram-positive cardiovascular infection with daptomycin (DAP) experienced a lower … Webpulmonary toxicity is accounted by two mechanisms: drug accumulation near epithelial alveolar surfaces causing injury and daptomycin-surfactant interaction altering lipid integrity stimulating an inflammatory response [1]. These mechanisms can cause life threatening consequences with the development of EP. Systematic review of … china lake naws commissary

Possible Hepatotoxicity Associated With Daptomycin: A Case

WebSep 29, 2024 · He was started on daptomycin for methicillin-resistant Staphylococcus aureus (MRSA) right fifth metatarsal osteomyelitis. Laboratory testing revealed severe hyperkalemia of 7.5 mEq/L (normal range: 3.3-5.1) and acute kidney injury (AKI) stage 1 associated with a substantial elevation in serum creatine kinase (CK). WebNov 10, 2024 · Daptomycin, a lipopeptide drug targeting methicillin-resistant Staphylococcus aureus, is used to treat skin and soft tissue infections, ... A risk prediction flowchart of vancomycin-induced acute kidney injury to use when starting vancomycin administration: a multicenter retrospective study. Antibiotics. 2024; 9: 920. doi:10.3390 ... WebDaptomycin is associated with a number of adverse effects including eosinophilic pneumonia, hypersensitivity reaction, myopathy, rhabdomyolysis, headache and transaminitis. The adverse effects of … china lake geothermal power plant

Drug-Induced Kidney Disease Associated With Selected …

Daptomycin induced kidney injury

Rhabdomyolysis and acute renal failure in a patient treated with daptomycin

WebAlthough daptomycin is a well-tolerated antibacterial agent, clinicians should consider periodic monitoring of liver function and renal function tests to identify potential adverse … WebJan 12, 2006 · Recently, a case of muscle pain and elevation of CPK induced by daptomycin was reported followed by another case in which myopathy was associated with elevation of CPK as well as liver enzymes. 1, 6 In the first case, CPK elevation was moderate and there was no mention of alteration in liver or kidney function. The second …

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WebNov 4, 2024 · Given the frequent prescribing of vancomycin, delineating the exposure–nephrotoxicity relationship is imperative to prevent unnecessary kidney injury. Clinical studies have demonstrated that vancomycin-associated acute kidney injury (AKI) prevalence ranges from 5% to 43% [ 3 ]. WebMar 28, 2024 · Daptomycin use is a known cause of rhabdomyolysis; its role in liver injury is less certain. We report a case of daptomycin-induced rhabdomyolysis with liver injury.

WebMay 1, 2024 · Therefore, we aim to discuss the mechanisms of drug-induced kidney disease with regard to vancomycin, daptomycin, and ceftaroline and to provide insight … WebJun 1, 2012 · While undifferentiated myoblasts were resistant to daptomycin induced injury up to concentrations of 6 mg/ml, differentiated myocytes were damaged with 2 mg/ml. Moreover, already 0.75 mg/ml daptomycin were sufficient to suppress spontaneous contractility [ 34 ].

WebDaptomycin is known to be associated with several side effects, including eosinophilic pneumonia, anaphylaxis/hypersensitivity reaction, myopathy, peripheral neuropathy, … WebJun 1, 2010 · Acute interstitial nephritis (AIN) represents a frequent cause of acute kidney injury, accounting for 15–27% of renal biopsies performed because of this condition. By and large, drug-induced AIN is currently …

WebMar 16, 2024 · There are 3 daptomycin eosinophilic syndromes: peripheral eosinophilia, primary DPE occurring about 4 weeks into therapy, and re-exposure DPE. Elevated peripheral eosinophilia ≥5% was a risk factor for both primary and re-exposure DPE, but still identified about half the cases.

Web2 days ago · LiverTox® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and … china lake nwc and otsWebFeb 12, 2024 · Vancomycin-Associated Acute Kidney Injury: A Narrative Review from Pathophysiology to Clinical Application Vancomycin is the most frequently used antibiotic, accounting for up to 35% of hospitalized patients with infection, because of its optimal bactericidal effectiveness and relatively low price. grails empty chamberWebMar 28, 2024 · Daptomycin is reported to cause an elevation in creatine kinase levels, although frank rhabdomyolysis is rare. An even more infrequent occurrence is the … china lake pass and id officeWebSep 11, 2024 · The temporal association between the initiation of Daptomycin and the onset of PRES is highly suggestive of causality, and this is further supported by clinical … grails dbcreateWebSep 29, 2024 · He was started on daptomycin for methicillin-resistant Staphylococcus aureus (MRSA) right fifth metatarsal osteomyelitis. Laboratory testing revealed severe … china lake plane crashWebMar 21, 2024 · Daptomycin was discontinued and the patient was started on treatment for rhabdomyolysis. Despite aggressive hydration and diuresis, CPK and urine myoglobin … grails forwardWebSafety outcomes with high-dose daptomycin in patients with acute kidney injury and/or end-stage renal disease In a cohort of patients with severe renal dysfunction treated with … grails cookie