Web18 de mai. de 2024 · The HOVON-141/VIsion trial is a phase-II trial in relapsed or refractory (R/R) CLL patients, evaluating the efficacy of MRD-guided ibrutinib and venetoclax combination treatment [ 11, 12 ]. To... WebPatients without prior treatment for CLL (Corticoid treatment administered due to necessary immediate intervention is allowed; within the last 10 days before start of study treatment only dose equivalents of maximum 20 mg prednisolone are permitted); Patients aged ≥ 18 years, not fit for FCR-like regimens, according to the treating physician;
Clinicobiological characteristics and treatment efficacy of novel ...
Web7 de abr. de 2024 · The phase II HOVON 139/GiVe trial is the first available study to investigate the efficacy and safety of a predetermined 12-cycle venetoclax consolidation compared to MRD-guided venetoclax consolidation following a fixed-duration combination therapy of venetoclax plus obinutuzumab. Web12 de abr. de 2024 · The authors demonstrate that CLL with the IGLV3-21R110 is typified by a distinct molecular profile. how: These observations require further validation in a larger series as the number of IGLV3-21R110 patients that the authors evaluated was limited especially in the HOVON-139/GIVE trial. SUMMARY pool pentair filter return sock
HOVON HO158 CLL - Trials
Web11 de nov. de 2024 · A phase 1 and 2a open-label study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity and antitumor activity of LAVA … Web30 de nov. de 2024 · Naam. ACE-CL-311. Titel. A Randomized, Multicenter, Open-Label, Phase 3 Study to Compare the Efficacy and Safety of Acalabrutinib (ACP-196) in Combination with Venetoclax with and without Obinutuzumab Compared to Investigator’s Choice of Chemoimmunotherapy in Subjects with Previously Untreated Chronic … Web23 de jun. de 2024 · The HOVON CLL working group designed the guideline; LvdS wrote the manuscript under supervision of GR with contributions from all authors, who also interpreted the data, and read, commented on, and approved the final version of … pool perfect phosfree 3l